Endoret Plasma Therapy

Endoret PRGF is a biolifting and skin rejuvenation procedure, available in two types:

1) Endoret Plasma Therapy (Endoret)

This is an innovative technique involving the injection of the patient’s own plasma into areas of the face, neck, décolleté, or scalp. While similar to classic plasmolifting, Endoret delivers a significantly more noticeable and longer-lasting rejuvenating effect due to the use of plasma enriched with platelets. The extraordinary results are achieved by isolating 2.5 times more of the body’s own growth factors from the blood plasma. These proteins stimulate the production of new collagen, making the skin firm and radiant.

Endoret plasma therapy provides deep rejuvenation and healing because the growth factors are highly active. They stimulate the synthesis of elastin, collagen, and hyaluronic acid at the cellular and molecular level. A 100% concentration of viable platelets supports angiogenesis—the formation of new blood vessels—which is essential for tissue regeneration. The outcome is a visible, comprehensive effect: lifting, rejuvenation, and anti-aging.

Advantages of Endoret Plasma Therapy:

• Safety: Endoret guarantees 100% biocompatibility, eliminating the risk of allergic reactions. No additives are used—only natural growth factors. During the procedure, the blood is not exposed to air. More than 100 clinical studies confirm its absolute safety.

• Purified Plasma: The plasma is separated into fractions, allowing leukocytes (white blood cells) to be removed. This is crucial since leukocytes can cause side effects such as irritation, inflammation, and breakouts at the injection site.

• Effectiveness: Endoret is clinically proven to be 2.5 times more effective than standard plasmolifting. Once the plasma is fractioned, a patented serum is added to the desired component, boosting the production of natural growth factors by 2–3 times. Thanks to modern technology, Endoret offers a real alternative to plastic surgery.

• Regeneration: Platelets in high concentration accelerate tissue regeneration due to their angiogenic and self-repair capabilities. PRP Endoret is highly effective after skin injuries, surgery, and chemical peels.

• Speed of Procedure: Blood collection and preparation take just 8 minutes, and the procedure itself only 20 minutes. The process follows a strict protocol and uses advanced equipment. No downtime is needed—any injection marks disappear within an hour.

• Wide Applications: PRP Endoret is used in anti-aging therapy (eliminates wrinkles, improves skin elasticity and tone), acne and post-acne treatment (thanks to its bacteriostatic effect), trichology (hair treatment), and scar and stretch mark therapy.

• Certification: Endoret is the only plasma therapy certified by both the EU (BTI Biotechnology Institute, Spain, 20.03.2015) and the USA (FDA), as well as in Ukraine (UA.TR.116).

Endoret Plasma Therapy Course: 3 procedures are recommended.

2) Endoret Biofiller (Biogel)

Used as a dermal filler to eliminate wrinkles on the face and neck. Growth factors derived from the patient’s own plasma are added to a special gel base. Unlike traditional fillers that simply fill in wrinkles, the biofiller provides a more pronounced and longer-lasting effect by strengthening and rejuvenating the skin.

Target areas for Endoret biofiller:

• Nasolabial folds

• Fine lines around the eyes

• Marionette lines (around the mouth)

Advantages of Endoret Biofiller:

• Safety: Being an autologous filler, it eliminates the risk of allergic reactions.

• Longer-lasting results: The effects are more durable than traditional fillers.

• Minimal downtime: Injection marks fade within a few hours.

• Comprehensive rejuvenation: In addition to filling wrinkles, the skin becomes more youthful and radiant thanks to the action of growth factors.

Doctors at ANACOSMA often combine both techniques—starting with plasma therapy, then following up with Endoret biogel to fill wrinkles. The study shows this combined method provides a synergistic effect, enhancing both skin quality and soft tissue restoration in a short time.

Where is PRGF Endoret Plasma Therapy Used?

1. In Anti-Aging Therapy (Face, Neck, Décolleté, Hands):

• Improves skin firmness and elasticity

• Reduces fine lines

• Brightens skin affected by photoaging (pigmentation)

2. For Acne and Scar Treatment:

• Treats acne (Grade 1–2)

• Fades post-acne pigmentation

• Enhances the skin’s protective function

• Treats and prevents atrophic scars and stretch marks

3. In Trichology (Hair & Scalp Care):

• Treats and prevents atrophic scars and stretch marks

• Treats alopecia of various origins

• Strengthens hair follicles

• Improves hair growth and texture

4. In Plastic Surgery:

• Speeds tissue regeneration and healing

• Reduces postoperative pain and swelling

• Accelerates recovery (decreases infection risks and supports faster scar healing as confirmed by clinical studies)

Additionally, Endoret is widely used in orthopedics. Clinical studies  show that PRGF plasma therapy is significantly more effective than hyaluronic acid in treating knee joint issues.

How many Endoret plasma therapy sessions are needed?
It depends on the treatment goals:

• Anti-aging therapy: A course of 3 sessions with 1-month intervals. Visible improvements—brighter tone, smoother fine lines—are seen even after the first session.

• Acne and scar treatment: Recommended course of 3–6 sessions, spaced 3–4 weeks apart.

• Trichology (hair treatment): Recommended course of 5–6 sessions, spaced 3–4 weeks apart.

Important: At ANACOSMA, to ensure patient safety, rapid tests for HIV, Hepatitis B and C, and syphilis (Treponema) are performed before the first blood draw for plasma therapy.